Endocrine Abstracts

Introduction: Autoimmune thyroiditis is a disease where the immune system attacks and destroys the thyroid gland. If the pathological exam lacks, the serum antithyroid antibodies are used to diagnose it. Also a useful tool is represented by the anterior cervical ultrasound.Aim: Our aim was to study the ultrasound phenotype in patients diagnosed with Hashimoto’s thyroiditis (HT+).Material and methods: The patients were investig...

Among hypertensive population, almost 10% have primary hyperaldosteronism. In these cases, most abnormalities are related to hypokaliemia with progressive or acute onset of the symptoms.We present the case of 34-year-old male patient, without significant pathological history, with a sudden neurological episode, dominated by tetraplegia and mild elevated blood pressure. Extremely low values of serum potassium are found. Diabetes mellitus is also discovere...

Introduction: Galactocele is a rare form of cystic, benign lesion of the breast, occurring when a mammary duct becomes obstructed and over filled with milk. It usually appears in postpartum women, either lactating or not, but it is extremely rarely seen in postmenopausal women or in men.Subject: We present the case of a 37-year-old female patient, nullipara, diagnosed with a microprolactinoma 18 months ago, and treated with bromocriptine since then (7.5 ...

Introduction: Left hepatic lobe volume (LHLV) has been associated with hyperinsulinemia and insulin resistance in obese women.Aim: To study the correlation between LHLV and body weight, regardless the weight and gender of the patient.Subjects and methods: The left hepatic lobe was evaluated with an echographic probe of 3.5 MHz. The LHLV (cm3) was calculated with the formula: antero-posterior diameter (length)×longit...

Aim: To re-evaluate the prevalence of autoimmune associations in Hashimoto’s thyroiditis (HT).Subjects and methods: The study was performed on 469 consecutive patients with HT and 536 without. The diagnosis of HT was based on an antithyroperoxydase antibodies (ATPO) level above 34 IU/ml. The subjects were evaluated for other associated immune diseases. The statistical analysis used the χ2 test.Results: F...

Introduction: Premature ovarian failure (POF) may be a part of autoimmune polyglandular syndromes that involves multiple endocrine and systemic conditions due to autoimmunity.Material and methods: We aim to present the case of a young women diagnosed with POF and Schmidt syndrome. The patient was followed in different tertiary centers of endocrinology. The informed consent was obtained.Case report: A 31-year old patient with no pri...

Introduction: Menopausal adrenal tumours may be elements of a complex panel of co-morbidities. Some of these are represented by the presence of a second pathology requiring surgery at the kidney level.Aim: We aim to introduce a series of two cases involving menopausal women who were referred for specific endocrine assays after they had a unilateral nephrectomy (UN).Method: This is a cases series observational study. The patients ga...

Introduction: Even if breast cancer is rare cause of pituitary metastases, the diagnosis of a pituitary adenoma, shortly after surgery for breast cancer, raises suspicion of a possible secondary determinations.Material and method: This is a case report revealing the medical history and endocrine profile of a female with breast cancer and pituitary macroadenoma.Case data: A 64-year old non-smoking female (with menopause at age of 52...

Introduction: Cushing’s disease (CD) is caused by high adrenocorticotropic hormone (ACTH), usually by a pituitary microadenoma.Material and method: This is a case report investigated in several Romanian centers by performing: morning plasma cortisol, circadian rhythm of plasma cortisol, plasma ACTH, dexamethasone (DXM) suppression tests.Case data: A 57-year female, known with hypertension and osteopenia, was ...

Introduction: Cushing’s disease (CD) in youth represents a challenge especially related to the therapy and long-term management.Materials and methods: We report the medical history of a child with CD who was followed-up for 7 years. Suggestive endocrine panel and imagery is exposed.Case presentation: A 19-year female was diagnosed at age of 12 with CD. Clinical assessment revealed: weight gain, headache, hyperpigmentation pred...